Eminem is back, firing away at celebrities

Britney, Lindsay, Sarah Palin and more targeted in first video off ‘Relapse’

Celebrities beware: Eminem is back and he's got more bite than ever.

In the first video from his upcoming album, "Relapse," the rapper fires away mercilessly at celebrity culture, targeting a list of tabloid faves including Bret Michaels, Jessica Simpson, Sarah Palin, Kim Kardashian, Britney Spears, Lindsay Lohan and Amy Winehouse.

A blond-wig wearing Eminem, in the guise of "Rock of Love's" Michaels, opens the "We Made You," video, which premiered on MTV Tuesday morning, and so begins a romp through pop culture that offers a portly Simpson look-a-like gyrating in Daisy Dukes; a Palin clone laying prone on a desk in a bustier as a polar bear and Eskimo dance nearby; and Kardashian meeting a "Fargo"-like fate in a wood chipper (which converts her to cash).

Ripping into his rap, he sings: "Back by popular demand/ Now pop a little Zantac/ Or antacid if you can/ You're ready to tackle any task that is at hand/ How does it feel? Is it fantastic, is it grand?"

"There's some celebrity bashing in it," Eminem admitted in a clip from the set, according to MTV News. "I wanna say it's not necessarily intentional bashing in it; it's not necessarily taking deliberate shots at people. ... Yes, it is. What the f--- am I talking about?"

The erstwhile Slim Shady plays a host of characters in the video (his first solo effort since 2003) including Simpson beau Tony Romo, Jailhouse Rock Elvis, a soulful John Mayer romancing Jennifer Aniston, a bare-chested lumberjack seducing Palin, Winehouse's estranged ex Blake Fielder-Civil, Dustin Hoffman's "Rainman" character (with a Dr. Dre cameo in Tom Cruise's role) and, in a series of “Star Trek”-inspired clips, a Vulcan-death-grip-wielding Mr. Spock.

"Relapse," Eminen's first studio album since 2004's "Encore," is due out May 19.